Opioid-induced delirium comes on when one has taken too many opioids, causing an alteration in mental status.
Often times when we are seeing stroke patients they may come in with an overdose of opioids that causes stroke or mental status changes. This is often mistaken as a stroke. Many of our patients who need Narcan are actually given in this case.
The loss of consciousness is secondary to mu-opioidW receptors causing respiratory depression which can cause anoxia.
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