Ultra Rapid Opioid Detoxification
- Admin
- Nov 28, 2020
- 2 min read
Updated: Dec 16, 2020
Opioid dependence is a very difficult disease to be treated. (Singh J, 2004) New ideas are being added in its process of treatment. Some of the new management procedures used now are rapid opioid detoxification and ultra-rapid opioid detoxification. (Charney et al., 1986) The treatment and management of opioid withdrawal are very stressful. (LeoLinzmayerJosefGrünberger, n.d.) Some patients do not try to leave the opioids due to such painful sufferings. That's why scientists tried to make a strategy to reduce the duration of suffering. Blachley et al was among the pioneers who started administering anesthesia in treatment for making the management quite easy.
Discovery
This method of using anesthesia was first developed by Loimer. (Loimer et al., 1989) Afterward, several modifications led to the development of a new technique known as Ultra-RAPID Opioid Withdrawal.
Aims and Goals
· To decrease the duration of the detoxification process
· To reduce the physical discomfort
· To decrease the time lag between last induction and maintenance dose
Spanagel et al, (Spanagel, 2000) reports that there is no evidence of the redisposition of normal neurobiological homeostasis with an opioid antagonist. But, the use of anesthesia has shown a decrease in withdrawal signs. (Streel & Verbanck, 2003)There is an explanation that the anesthesia interferes with the glutamate, which in return affects the noradrenergic over-activity which reduces the withdrawal symptoms.
Classification
Johnson and Carrclassified the naltrexone-induced process as under: (CARR, 2003)

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