The drug buprenorphine is used for the management of opioid disorder. The uses of buprenorphine are dominant over its side effects. The drug buprenorphine is used for the helps in the reduction of cravings without having harmful effects and euphoria. The FDA of United States approved the use of this drug for the treatment of opioid withdrawal.

It has high affinity for mu-opioid receptors as compared to other drugs.

Buprenorphine formulations

It is available in two ways which are “Buprenorphine mono-product and buprenorphine/naloxone combination.” The combination of this drug is available in the form of sublingual tablet and is contraindicated for pregnant females.

Treatment goals and patient selection

Buprenorphine is used for patients who are not hypersensitive to opioid agonists. A consent form is signed by the patient before the treatment of disorders.


· For suppression of opioid withdrawal

· For blocking the effects of illicit opioids

· For reduction of cravings

· For promotion of patient engagement in psychosocial intervention

There is enough evidence on the effectiveness of buprenorphine. (T.V. Parran,b,e,* C.A. Adelman,a,b B. Merkin,b,e M.E. Pagano,d R. Defranco,b R.A. Ionescu, 2010)


Careful monitoring is required for the patient receiving

· Alcohol

· Sedative

· Hypnotics

· Anxiolytics

Course of Treatment

The trained physicians are allowed to prescribe narcotics for the treatment of this disorder according to DATA 2000. (Food and Drug Administration (FDA) to treat Opioid Use Disorder (OUD), 2020)


Patients need to experience the withdrawal symptoms before starting this drug otherwise the patient may experience precipitated withdrawal.

Buprenorphine is